The effect of testosterone propionate, durabolin and deca-durabolin on the thymus of the male rats.

ABSTRACT

Twenty-five male rats, 26-27 days of age, average weight 61.62 gm. were divided into 4 groups. Rats of each group were injected with subcutaneously every second day 1 mg. one of the following drugs durabolin, Deca-durabolin or Testosterone propionate, and the last group, as normal control, was uninjected. All rats were sacrificed at 54-55 days of age. The thymus glands were weighed and histological appearances were observed. This study showed that thymic weights of all injected groups were less than that of the control, indicating that all 3 drugs caused the thymus gland to involute faster than normal. In comparing the weight and histological appearances of effect on the thymus gland.