A case of acute myeloid leukemia-M2 with trisomy 4 in addition to t(8;21).
Indian J Hum Genet
;
2008 Jan; 14(1): 20-22
Artigo
em Inglês
| IMSEAR
| ID: sea-138845
ABSTRACT
t(8;21)(q22;q22) is the most frequently observed karyotypic abnormality associated with acute myeloid leukemia (AML), specifically in FAB-M2. Short-term unstimulated bone marrow (BM) and peripheral blood lymphocyte culture showed 47,XX, +4,t(8;21) in all metaphase plates; and interphase and metaphase results of AML-ETO fusion was positive and trisomy of 4 was confirmed with WCP probes. Trisomy 4 in AML with t(8;21) is a rare numerical abnormality. Here we present such case of patient which may constitute a distinctive subtype.
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Índice:
IMSEAR (Sudeste Asiático)
Idioma:
Inglês
Revista:
Indian J Hum Genet
Ano de publicação:
2008
Tipo de documento:
Artigo
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