A new recurring chromosome 13 abnormality in two older patients with de novo acute myeloid leukemia: An Indian experience.
Indian J Hum Genet
; 2009 Sept; 15(3): 137-139
Article
em En
| IMSEAR
| ID: sea-138886
We report here two cases of trisomy 13 in acute myeloid leukemia M1 subtype. short-term unstimulated bone marrow and peripheral blood lymphocyte culture showed 47, XY, +13 in all metaphase plates and trisomy 13 was confirmed with whole chromosome paint probes. Trisomy 13 in AML-M1 is a rare numerical abnormality. This is the first Indian report of sole trisomy 13 in AML-M1. Here, we present two cases of elder male patients, which may constitute a distinct subtype.
Palavras-chave
Texto completo:
1
Índice:
IMSEAR
Assunto principal:
Trissomia
/
Cromossomos Humanos Par 13
/
Idoso
/
Humanos
/
Masculino
/
Células da Medula Óssea
/
Linfócitos
/
Leucemia Mieloide Aguda
/
Aberrações Cromossômicas
/
Hibridização in Situ Fluorescente
País/Região como assunto:
Asia
Idioma:
En
Revista:
Indian j. hum. genet
Ano de publicação:
2009
Tipo de documento:
Article