Wheat threshing dust--a "new allergen" in April-May nasobronchial allergy.
Indian Pediatr
;
1996 Jul; 33(7): 566-70
Artigo
em Inglês
| IMSEAR
| ID: sea-14110
ABSTRACT
OBJECTIVE:
To identify the allergen(s) responsible for mid April-mid May nasobronchial allergy seen in North India.DESIGN:
Case control study.SETTING:
Children living in and around Chandigarh (urban, rural).SUBJECTS:
39 children suffering from wheat harvest period (mid April-mid May) respiratory allergy along with randomly selected controls.METHODS:
Aerobiological surveys were done from March to June for identification of prevailing allergens for performing allergy tests. Patients were subjected to skin tests (ST), nasal provocation tests (NPT) and bronchial provocation tests (BPT) with extracts prepared from identified pollens and fungal spores. Specific IgE (SIgE) was assayed by ELISA and comparison between pre-season, season and post-season values made.RESULTS:
81% patients had ST positive to antigen of wheat threshing dust (WTD), 30% to fungal antigens, 14% to wheat dust antigens and none to the wheat plant (WP) antigens. Nasal provocation test and bronchial provocation tests were also positive to WTD in 80% and 66% patients, respectively. WTD SIgE was demonstrated in 77% of ST positive patients.CONCLUSIONS:
These in vivo and in vitro tests confirm wheat threshing dust as a major causative inhalant allergen for the April-May nasobronchial allergy; in addition, fungal allergens also play a role in 1/3rd of these patients.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Hipersensibilidade Respiratória
/
Estações do Ano
/
Triticum
/
Humanos
/
Estudos de Casos e Controles
/
Criança
/
Análise de Variância
/
Adolescente
/
Agricultura
/
Poeira
Tipo de estudo:
Estudo observacional
/
Fatores de risco
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Indian Pediatr
Ano de publicação:
1996
Tipo de documento:
Artigo
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