Transfusion-induced hemoglobinopathy in patients of beta-thalassemia major.
Indian J Pathol Microbiol
;
2011 Jul-Sept 54(3): 609-611
Artigo
em Inglês
| IMSEAR
| ID: sea-142058
ABSTRACT
Apparent hemoglobinopathy acquired after blood transfusion is an uncommon cause of diagnostic dilemma resulting in repeated testing and delay in the diagnosis. Out of the 1530 hemoglobin (Hb)- high-performance liquid chromatography (HPLC) performed at our hospital (May 2009 to April 2010), 3 pediatric cases of thalassemia major were detected having posttransfusion hemoglobinopathy with HbS ranging from 9.9% to 18.5%. In all three cases, there was no variant hemoglobin in earlier documented Hb-HPLC. It is important to be aware of and consider apparent transfusion-induced hemoglobinopathy in patients with unusual percentage of variant hemoglobin to avoid unnecessary treatment and counseling.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Transfusão de Sangue
/
Humanos
/
Masculino
/
Hemoglobinas
/
Pré-Escolar
/
Cromatografia Líquida de Alta Pressão
/
Talassemia beta
/
Hemoglobinopatias
/
Lactente
Idioma:
Inglês
Revista:
Indian J Pathol Microbiol
Ano de publicação:
2011
Tipo de documento:
Artigo
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