Protein C and protein S: Causative factor for developing a hemorrhagic infarct in a HbE/Beta thalassemia child.
Indian J Pediatr
;
2010 Mar; 77(3): 316-317
Artigo
em Inglês
| IMSEAR
| ID: sea-142529
ABSTRACT
A 10-yr-old HbE/Beta thalassemia child who developed subacute to chronic occipitotemporal hemorrhagic infarct with smaller chronic infarct with gliotic changes in the left frontal periventricular white matter. Genetic tests showed that patient was positive for HbE and IVS1-5 mutation and was negative for thrombogenic mutations. Hemorrhagic infarct was confirmed by magnetic resonance imaging study. Antigenic levels of Protein C and Protein S were low. Based on these outcomes, it was concluded that Protein C and Protein S deficiency were the causative factor for developing hemorrhagic infarct in the HbE/ Beta thalassemia patient.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Humanos
/
Masculino
/
Imageamento por Ressonância Magnética
/
Hemorragia Cerebral
/
Infarto Cerebral
/
Criança
/
Talassemia beta
/
Deficiência de Proteína S
/
Deficiência de Proteína C
Idioma:
Inglês
Revista:
Indian J Pediatr
Ano de publicação:
2010
Tipo de documento:
Artigo
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