Complement-dependent lymphocytotoxicity crossmatch in deceased donor renal transplant: A single institutional experience.
Indian J Med Microbiol
;
2011 Oct-Dec; 29(4): 414-417
Artigo
em Inglês
| IMSEAR
| ID: sea-143867
ABSTRACT
Complement-dependent lymphocytotoxicity crossmatches (n=217) between 47 deceased donors and 150 potential renal recipients were retrospectively studied. A negative cross match was reported in 48 (22.1%), doubtful positive in 126 (58.1%), weakly positive in 32 (14.7%) and positive in 11 (5.1%). No autoantibodies were detected. Renal transplantation was performed in 35.5% of the potential recipients. There was no incidence of hyperacute rejection. The graft survival rate was 88% at 15 months of follow up. The study concludes that a negative pretransplant lympocytotoxicity crossmatch using the basic National Institute of Health technique eliminates hyperacute rejection, but carries drawbacks, which require modification and supplementation with more sensitive and specific assays.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Idoso
/
Feminino
/
Humanos
/
Masculino
/
Proteínas do Sistema Complemento
/
Testes Imunológicos de Citotoxicidade
/
Teste de Histocompatibilidade
/
Criança
/
Pré-Escolar
/
Estudos Retrospectivos
Tipo de estudo:
Estudo observacional
Idioma:
Inglês
Revista:
Indian J Med Microbiol
Assunto da revista:
Microbiology
Ano de publicação:
2011
Tipo de documento:
Artigo
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