Pathogenomics of uropathogenic Escherichia coli.
Indian J Med Microbiol
;
2012 Apr-June; 30(2): 141-149
Artigo
em Inglês
| IMSEAR
| ID: sea-143935
ABSTRACT
Subset of faecal E. coli that can enter, colonize urinary tract and cause infection are known as uropathogenic E. coli (UPEC). UPEC strains act as opportunistic intracellular pathogens taking advantage of host susceptibility using a diverse array of virulence factors. Presence of specific virulence associated genes on genomic/pathogenicity islands and involvement of horizontal gene transfer appears to account for evolution and diversity of UPEC. Recent success in large-scale genome sequencing and comparative genomics has helped in unravelling UPEC pathogenomics. Here we review recent findings regarding virulence characteristics of UPEC and mechanisms involved in pathogenesis of urinary tract infection.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Infecções Urinárias
/
Virulência
/
Humanos
/
Evolução Molecular
/
Transferência Genética Horizontal
/
Fatores de Virulência
/
Ilhas Genômicas
/
Infecções por Escherichia coli
/
Escherichia coli Uropatogênica
Idioma:
Inglês
Revista:
Indian J Med Microbiol
Assunto da revista:
Microbiology
Ano de publicação:
2012
Tipo de documento:
Artigo
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