Chronic eosinophilic leukemia with a unique translocation.
Indian Pediatr
;
2009 June; 46(6): 525-527
Artigo
em Inglês
| IMSEAR
| ID: sea-144063
ABSTRACT
We report a case of chronic eosinophilic leukemia in a 9 year old girl who presented with anemia, thrombocytopenia, leucocytosis (mostly dysplastic eosinophils), lymphadenopathy and hepatosplenomegaly. There was no increase in blasts but myelofibrosis was seen in the bone marrow. A previously unreported translocation 46,XX,t(1;4)(q24;q35), was found on cytogenetic analysis and involvement of the myocardium was also present. Shortly after commencing steroids, the family abandoned therapy.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Translocação Genética
/
Feminino
/
Humanos
/
Ecocardiografia
/
Criança
/
Doença Crônica
/
Síndrome Hipereosinofílica
/
Eosinófilos
/
Glucocorticoides
/
Cardiomiopatias
Idioma:
Inglês
Revista:
Indian Pediatr
Ano de publicação:
2009
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS