Trans-differentiation of iris pigmented epithelial cells of Euphlyctis cyanophlyctis tadpoles into lens in vitro.
Indian J Exp Biol
;
2010 Jan; 48(1): 17-25
Artigo
em Inglês
| IMSEAR
| ID: sea-144091
ABSTRACT
Meshed pigmented iris epithelium along with neural retina of tadpoles of the frog Euphlyctis cyanophlyctis were found to undergo dedifferentiation and subsequently transdifferentiate into lens in culture medium. During lag period, depigmentation (dedifferentiation) occurred in many cells. When culture became confluent 3-4 weeks after seeding tiny lens like structures differentiated from foci of cultured pigmented iris epithelium cells. The percentage of lens formation was higher in vitamin A treated cases. The culture system appears to be a suitable for investigating the changes occurred during trans-differentiation of pigmented epithelial cells into lens.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Epitélio Pigmentado Ocular
/
Ranidae
/
Vitamina A
/
Iris
/
Técnicas de Cultura de Tecidos
/
Transdiferenciação Celular
/
Larva
/
Cristalino
/
Animais
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
2010
Tipo de documento:
Artigo
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