Brain tumor and Gliadel wafer treatment.
Indian J Cancer
;
2011 Jan-Mar; 48(1): 11-17
Artigo
em Inglês
| IMSEAR
| ID: sea-144405
ABSTRACT
Glioblastoma is a rapidly progressive and extremely fatal form of brain tumor with poor prognosis. It is the most common type of primary brain tumor. Even with the most aggressive conventional treatment that comprises surgery followed by radiotherapy and chemotherapy, most patients die within a year of diagnosis. Developments in molecular and cell biology have led to better understanding of tumor development, leading to novel treatment strategies including biological therapy and immunotherapy to combat the deadly disease. Targeted drug delivery strategies to circumvent the blood-brain barrier have shown efficiency in clinical trials. Gliadel wafer is a new approach to the treatment of glioblastoma, which involves controlled release delivery of carmustine from biodegradable polymer wafers. It has shown promising results and provides a silver lining for glioblastoma patients.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Neoplasias Encefálicas
/
Humanos
/
Carmustina
/
Antineoplásicos Alquilantes
/
Preparações de Ação Retardada
Idioma:
Inglês
Revista:
Indian J Cancer
Ano de publicação:
2011
Tipo de documento:
Artigo
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