Helicobacter pylori infection in relation to gastric cancer progression.
Indian J Cancer
;
2011 Jan-Mar; 48(1): 94-98
Artigo
em Inglês
| IMSEAR
| ID: sea-144418
ABSTRACT
Gastric cancer is a major cause of cancer death worldwide, especially in developing countries. The incidence of gastric cancer varies from country to country, probably as a result of genetic, epigenetic, and environmental factors. H. pylori infection is considered as a major risk factor in the development of gastric cancer. However, the scenario varies in Asian countries, exhibiting a higher rate of H. pylori infection and low incidence of gastric cancer, which could be attributed to strain-specific virulence factors and host genetic makeup. In this review, we discuss the various virulence factors expressed by this bacterium and their interaction with the host factors, to influence pathogenesis.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Neoplasias Gástricas
/
Humanos
/
Incidência
/
Helicobacter pylori
/
Infecções por Helicobacter
/
Progressão da Doença
Tipo de estudo:
Estudo de incidência
/
Estudo prognóstico
/
Fatores de risco
Idioma:
Inglês
Revista:
Indian J Cancer
Ano de publicação:
2011
Tipo de documento:
Artigo
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