Submacular hemorrhage: A study amongst Indian eyes.
Indian J Ophthalmol
;
2012 Nov-Dec; 60(6): 521-525
Artigo
em Inglês
| IMSEAR
| ID: sea-144912
ABSTRACT
Aim:
To evaluate the management outcomes amongst various treatment modalities for submacular hemorrhage (SMH) in Indian subjects. Settings andDesign:
Retrospective, single-center study. Materials andMethods:
Patients presenting with SMH between 1999 and 2006 were included. Treatment modalities included vitrectomy with subretinal recombinant tissue plasminogen activator (r-tPA) assisted SMH evacuation (group 1, n = 14); pneumatic displacement with intravitreal r-tPA and gas (group 2, n = 25); and pneumatic displacement with intraocular gas (group 3, n = 7). Favorable anatomical outcome was defined as complete displacement of SMH from fovea and favorable functional outcome was defined as a gain of >2 Snellen lines from the baseline. Kruskal–Wallis, analysis of variance (ANOVA), and Chi-square tests were used to compare the three groups, while Mann–Whitney and independent t-test were used to evaluate the influence of duration and size of SMH on outcomes.Results:
There was no difference amongst groups in terms of favorable anatomical (P = 0.121) or functional outcomes (P = 0.611). Eyes with median duration of SMH less than 7.5 days had a significantly higher probability of achieving favorable anatomical outcome compared to eyes with SMH >14.5 days (P = 0.042). However, duration of SMH did not influence functional outcome (P = 0.595). Similarly, size of SMH did not affect anatomical (P = 0.578) or functional (P = 0.381) outcome. Median follow-up was 31.5, 6.5, and 2.5 months in the three groups, respectively.Conclusions:
Co- existing posterior segment conditions and duration of SMH may influence the choice of treatment modality and treatment outcomes. Pneumatic displacement with r-tPA and r-tPA assisted vitrectomy appear to be favorable options for the management of SMH.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Vitrectomia
/
Humanos
/
Hemorragia Retiniana
/
Distribuição de Qui-Quadrado
/
Doenças da Coroide
/
Ativador de Plasminogênio Tecidual
/
Aneurisma
/
Degeneração Macular
Idioma:
Inglês
Revista:
Indian J Ophthalmol
Ano de publicação:
2012
Tipo de documento:
Artigo
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