Changes in protein subunits induced by endosulfan and fenvalerate in fresh water fish Labeo rohita through SDS-PAGE.

ABSTRACT

Fresh water fish Labeo rohita was exposed to two pesticides i.e., endosulfan an organchlorine and fenvalerate a synthetic pyrethroid. The 1/10th of 24 hr LC50 of endosulfan (0.0687 μ g l-1) and fenvalerate (0.0 474 μ g l-1) were selected as sub lethal concentrations. The fish were exposed to sublethal concentrations for one week and the changes in the tissue proteins of vital organs such as brain, liver, gill and muscle were studied under SDS-PAGE. The protein subunits were identified by running marker proteins parallel and Rm values were calculated accordingly. The changes in the protein banding pattern are more pronounced in the fenvalerate exposure than endosulfan.