Evaluating the suitability of prediction equations for lung function in Indian children: a practical approach.
Indian Pediatr
;
2006 Aug; 43(8): 680-98
Artigo
em Inglês
| IMSEAR
| ID: sea-14707
ABSTRACT
OBJECTIVE:
Although several prediction equations to evaluate peak expiratory flow rate (PEFR) of Indian children are available in literature, clinicians and researchers need to make a logical choice of which equation to use as reference. The aim was to demonstrate a practical approach to making such a logical choice by using prediction equations on our study population.METHODS:
Eighteen linear regression equations generated on Indian children were chosen from available literature. PEFR measured on a Wright peak flow meter on 81 boys and 60 girls, aged between 8 and 13 years, was compared with the predicted values obtained from the equations. Data was systematically analyzed for the extent of over-estimation and under-estimation, correlation between the predicted and measured values and bias and limits of agreement using Bland-Altman plots.RESULTS:
The correlation between observed and predicted values using the eighteen equations ranged between 0.616 and 0.797 (for all P < 0.001). The Bland-Altman plots indicated that for all but three equations in boys and three equations in girls, lower measured values of PEFR were associated with higher predicted values. A final choice of a reference prediction equation was based on a combination of factors which included a high correlation between actual and predicted PEFR values, the bias of the estimate, the limits of agreement and the extent to which equations over or under-estimated PEFR.CONCLUSION:
A practical approach to evaluate the applicability of prediction equations on an independent data set has been demonstrated.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Valores de Referência
/
Testes de Função Respiratória
/
Instituições Acadêmicas
/
Feminino
/
Humanos
/
Masculino
/
Criança
/
Pico do Fluxo Expiratório
/
Capacidade Pulmonar Total
/
Capacidade Vital
Tipo de estudo:
Estudos de avaliação
/
Estudo prognóstico
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Indian Pediatr
Ano de publicação:
2006
Tipo de documento:
Artigo
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