Impact of monitoring cerebral oxygen saturation on the outcome of patients undergoing open heart surgery.
Ann Card Anaesth
;
2013 Apr; 16(2): 102-106
Artigo
em Inglês
| IMSEAR
| ID: sea-147237
ABSTRACT
Aims and Objectives:
We studied the usefulness of regional cerebral oxygen saturation (rSO 2 ) monitoring during cardiopulmonary bypass (CPB) and evaluated effects of cerebral oxygen desaturation on the postoperative neurological outcome. Materials andMethods:
100 patients were randomly allocated to either control or intervention group. In the control group rSO 2 was recorded continuously, but the attending anesthesiologist was blinded. In the intervention group specific interventions were initiated in case of cerebral desaturation. Neurocognitive testing was done using a simplified antisaccadic eye movement test (ASEM) and mini-mental state examination (MMSE). Data was analyzed using Chi-square test, and unpaired t-test.Results:
In both the groups rSO 2 declined during CPB. The decrease in rSO 2 was significant ( P < 0.001) in the control group compared to the intervention group. In the intervention group the rSO 2 mainly responded to an increase in mean arterial pressure. The area under the curve below threshold rSO 2 was significantly more ( P < 0.0001) in the control group compared to intervention group and a significant decrease in the MMSE and ASEM scores occurred in control group at one week and three months postoperatively.Conclusions:
Monitoring of rSO 2 during CPB can significantly decrease the incidence of postoperative neurocognitive decline.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Oxigênio
/
Encéfalo
/
Feminino
/
Humanos
/
Masculino
/
Ponte Cardiopulmonar
/
Monitorização Intraoperatória
/
Adulto
/
Procedimentos Cirúrgicos Cardíacos
/
Pessoa de Meia-Idade
Tipo de estudo:
Estudo prognóstico
Idioma:
Inglês
Revista:
Ann Card Anaesth
Ano de publicação:
2013
Tipo de documento:
Artigo
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