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Impact of monitoring cerebral oxygen saturation on the outcome of patients undergoing open heart surgery.
Ann Card Anaesth ; 2013 Apr; 16(2): 102-106
Artigo em Inglês | IMSEAR | ID: sea-147237
ABSTRACT
Aims and

Objectives:

We studied the usefulness of regional cerebral oxygen saturation (rSO 2 ) monitoring during cardiopulmonary bypass (CPB) and evaluated effects of cerebral oxygen desaturation on the postoperative neurological outcome. Materials and

Methods:

100 patients were randomly allocated to either control or intervention group. In the control group rSO 2 was recorded continuously, but the attending anesthesiologist was blinded. In the intervention group specific interventions were initiated in case of cerebral desaturation. Neurocognitive testing was done using a simplified antisaccadic eye movement test (ASEM) and mini-mental state examination (MMSE). Data was analyzed using Chi-square test, and unpaired t-test.

Results:

In both the groups rSO 2 declined during CPB. The decrease in rSO 2 was significant ( P < 0.001) in the control group compared to the intervention group. In the intervention group the rSO 2 mainly responded to an increase in mean arterial pressure. The area under the curve below threshold rSO 2 was significantly more ( P < 0.0001) in the control group compared to intervention group and a significant decrease in the MMSE and ASEM scores occurred in control group at one week and three months postoperatively.

Conclusions:

Monitoring of rSO 2 during CPB can significantly decrease the incidence of postoperative neurocognitive decline.
Assuntos

Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Assunto principal: Oxigênio / Encéfalo / Feminino / Humanos / Masculino / Ponte Cardiopulmonar / Monitorização Intraoperatória / Adulto / Procedimentos Cirúrgicos Cardíacos / Pessoa de Meia-Idade Tipo de estudo: Estudo prognóstico Idioma: Inglês Revista: Ann Card Anaesth Ano de publicação: 2013 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Assunto principal: Oxigênio / Encéfalo / Feminino / Humanos / Masculino / Ponte Cardiopulmonar / Monitorização Intraoperatória / Adulto / Procedimentos Cirúrgicos Cardíacos / Pessoa de Meia-Idade Tipo de estudo: Estudo prognóstico Idioma: Inglês Revista: Ann Card Anaesth Ano de publicação: 2013 Tipo de documento: Artigo