Promoters, toll like receptors and microRNAs: A strange association.
Indian J Biochem Biophys
;
2013 Jun; 50(3): 169-176
Artigo
em Inglês
| IMSEAR
| ID: sea-147299
ABSTRACT
Toll-like receptors (TLRs) are proteins that play key role in the innate immune system. In the present study, ~1000 base pairs upstream are taken from the transcription start site of the various TLR genes (10 known) in human. About 40 microRNAs have been identified that share 12-19 nucleotide sequence similarity with the promoter regions of 10 TLRs. It is proposed that the microRNA performs potential role in identification of promoter sequence and initiation of transcription.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Humanos
/
Genoma Humano
/
Ativação Transcricional
/
Regiões Promotoras Genéticas
/
MicroRNAs
/
Receptores Toll-Like
/
Estudos de Associação Genética
Idioma:
Inglês
Revista:
Indian J Biochem Biophys
Ano de publicação:
2013
Tipo de documento:
Artigo
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