Effect of Naja naja Laurenti shed skin extract on estrous cycle, hormone - cytokine profiles, histopathology of ovary and uterus of Swiss albino mice.
Indian J Exp Biol
;
2013 Mar; 51(3): 235-240
Artigo
em Inglês
| IMSEAR
| ID: sea-147587
ABSTRACT
The snake shed skin though considered as biological waste products have been mentioned in folk and traditional medicine for treatment of ailments like skin disorders, parturition problems etc. Shedded skin extract (5 mg.kg-1, sc) did not produce any change in the estrous cycle of normal cycling female mice. However in 10 mg.kg-1, sc dose, the extract caused a temporary cessation of the estrous cycle at diestrous phase in normal cycling female mice for 10 days. SSAE (10 mg.kg-1, sc) caused a significant change in the level of LH, FSH, progesterone, estradiol, IL-1β, IL-6 and TNF-α. Histopathology of uterus and ovary showed structural disorientation in both. The results substantiate the influence of snake shed skin in mice reproductive cycle.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Ovário
/
Progesterona
/
Reprodução
/
Pele
/
Útero
/
Feminino
/
Regulação da Expressão Gênica
/
Citocinas
/
Elapidae
/
Ciclo Estral
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
2013
Tipo de documento:
Artigo
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