Protective effect of eicosapentaenoic acid-docosahexaenoic acid and α–linolenic acid rich phytosterol ester on brain antioxidant status and brain lipid composition in hypercholesterolemic rats.
Indian J Exp Biol
;
2013 Mar; 51(3): 241-248
Artigo
em Inglês
| IMSEAR
| ID: sea-147588
ABSTRACT
With a view to investigate the ameliorative effects of sitosterol esters against degenerative effects of hypercholesterolemia brain antioxidant enzyme assays, brain lipid profile, brain phospholipid compositional change and brain neurotransmitter concentrates (glutamic acid, asparctic acid, glycine) were measured in hypercholesterolemic rats. The results indicated that phytosterol esters have a role in countering hypercholesterolemia-related changes in the brain by decreasing the cholesterol levels, increasing the phospholipid levels and increasing the level of antioxidant enzymes. The results suggest that phytosterol esters may be of therapeutic significance and may offer new and effective options for the treatment of hypercholesterolemia-induced changes in the brain.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Fitosteróis
/
Ratos
/
Sitosteroides
/
Encéfalo
/
Masculino
/
Óleos de Peixe
/
Ácido Eicosapentaenoico
/
Ácidos Docosa-Hexaenoicos
/
Cromatografia
/
Ratos Wistar
Idioma:
Inglês
Revista:
Indian J Exp Biol
Ano de publicação:
2013
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS