Coumarin: Chemical and pharmacological profile.
Artigo
em Inglês
| IMSEAR
| ID: sea-151289
ABSTRACT
Coumarins are classified as a member of the benzopyrone family. all of which consist of a benzene ring joined to a pyrone ring. The benzopyrones can be subdivided into the benzoalfa- pyrones to which the coumarins belong and the benzo-gama-pyrones, of which the flavonoids are principal members. Umbelliferone, esculetin and scopoletin are the most widespread coumarins in nature. During the synthesis of these compounds ortho-hydroxylation should respectively take place on p-coumaric, caffeic and ferulic acid. The coumarins are of great interest due to their pharmacological properties. In particular, their physiological, bacteriostatic and anti-tumor activity makes these compounds attractive backbone derivatisation and screening as novel therapeutic agents.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Idioma:
Inglês
Ano de publicação:
2012
Tipo de documento:
Artigo
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