Anthelmintic and diuretic activity of bark extracts of Sterculia villosa.

ABSTRACT

The study was evaluated for diuretic and anthelmintic activity of the ethanolic extract of the barks of Sterculia villosa Roxb, (Sterculiaceae). The diuretic assay was done on both healthy wistar rats and rabbits. The dose used for the diuretic assay was 100, 200 & 400mg/kg of the extract. Compared to the control and standard drug furosemide (20mg/kg), the result of diuretic study showed dose dependent activity of the extracts. The result also indicated higher excretion of Na+, K+ & Cl- in urine. Pheretima posthuma, adult earthworms were used for anthelmintic activity and the results of anthelmintic assessment at the dose of 50, 100 & 200mg/ml showed significant activity compared with control and standard drug albendazole (10mg/ml).