Botulinum toxin – The new paradigm a review article.

ABSTRACT

Application of Botulinum toxin-A (Botox) in the field of dentistry is a new and upcoming. It acts by preventing the release of Acetylcholine at neuromuscular junction, which inhibits the contraction of muscles. This blockade is temporary, inhibiting the masticatory efficiency and function. It will return to its original levels once the effect of Botox has subsided, varying from three to four months. Botox is a viable treatment for many facial, TMD and oral dysfunctions when they are musculature based. Using Botox requires minimal training for a general dentist. It is most appropriate in patients who are refractory to other treatments.