Lipid peroxidation and total antioxidant capacity in health and disease - Pathophysiology and markers: An overview.

Free radicals play a significant role in the pathogenesis of many chronic diseases such as diabetes mellitus, cancer, chronic renal failure etc. Oxidative stress is defined as “a disturbance in the balance between the antioxidants and pro-oxidants (OFR in particular) with increased levels of pro-oxidants leading to potential damage. The knowledge about pathophysiology of lipid peroxidation and the oxidative stress biomarkers will definitely help the researchers to plan for focused study for better management of oxidative stress induced diseases.