Photochemotherapy (PUVA) in psoriasis and vitiligo.
Indian J Dermatol Venereol Leprol
;
2014 Nov-Dec; 80(6): 497-504
Artigo
em Inglês
| IMSEAR
| ID: sea-154881
ABSTRACT
Phototherapy with photochemotherapy (PUVA) is a well‑known and well‑studied modality for the treatment of psoriasis, which involves systemic or topical administration of chemicals known as psoralens and administration of ultraviolet light in increasing dosages after requisite time gap. PUVA is also used in the treatment of widespread vitiligo with moderately good results, though it is being surpassed by ultraviolet B (UVB), which is equally or slightly more efficacious with fewer side effects. PUVA induces repigmentation by varying mechanisms such as stimulation of melanogenesis, immunomodulation and activation of growth factors, though the exact mechanism is still speculative. There are various studies evaluating the efficacy of PUVA in psoriasis as well as in vitiligo, either alone or in combination with other immunosuppressants like azathioprine and calcipotriene.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Fotoquimioterapia
/
Furocumarinas
/
Psoríase
/
Raios Ultravioleta
/
Vitiligo
/
Humanos
Idioma:
Inglês
Revista:
Indian J Dermatol Venereol Leprol
Ano de publicação:
2014
Tipo de documento:
Artigo
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