Drug Eruptions Induced by Allopurinol Associated with HLA-B*5801.
Indian J Dermatol Venereol Leprol
;
2015 Jan-Feb; 81(1): 43-45
Artigo
em Inglês
| IMSEAR
| ID: sea-154971
ABSTRACT
Allopurinol, a drug commonly used for treating gout and hyperuricemia, is a frequent cause of drug eruptions. Recent investigations suggest that HLA‑B*5801 allele is a very strong marker for allopurinol‑induced cutaneous adverse drug reactions (cADRs). In this article we report two cases of allopurinol‑induced drug eruptions in patients carrying the HLA‑B*5801 allele and review the literature on the association between HLA‑B*5801 and allopurinol‑induced cADRs based on a MEDLINE and PubMed search.
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DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Idoso
/
Masculino
/
Antígenos HLA-B
/
Alopurinol
/
MEDLINE
/
Toxidermias
/
PubMed
/
Pessoa de Meia-Idade
Idioma:
Inglês
Revista:
Indian J Dermatol Venereol Leprol
Ano de publicação:
2015
Tipo de documento:
Artigo
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