A case of subacute cutaneous lupus erythematosus as a result of ranibizumab (Lucentis) treatment.

ABSTRACT

Cutaneous lupus erythematosus is a previously undiagnosed side‑effect of ranibizumab. Here, we present a case of an 82‑year‑old female Caucasian patient with wet age‑related macular degeneration. Following a single intraocular injection of Lucentis (ranibizumab), she developed a subacute cutaneous lupus erythematosus which, with treatment, took nearly 12 months to resolve. This shows that cutaneous lupus erythematosus is a potential side‑effect of many medications, including ranibizumab, as in our case and, in an aging population where polypharmacy is a growing reality, clinicians should be aware of how to diagnose and best manage such cases.