Population based family history analysis of Brahmins in a small town in India for the prevalence of type-2 diabetes mellitus.
Indian J Hum Genet
;
2013 July-Sept ;19 (3): 342-345
Artigo
em Inglês
| IMSEAR
| ID: sea-156588
ABSTRACT
OBJECTIVES:
The objective of this study is to determine the inheritance pattern of type‑2 diabetes and make stratification for the general population risk. MATERIALS ANDMETHODS:
A questionnaire was developed for o btaining the family history. Analysis of the data was carried out by using student and Chi‑square tests and for stratification; the guidelines of Scheuner et al. were followed.RESULTS:
The pattern of inheritance is the male sex specific (χ² =13.44). The mean age of onset of diabetes in parents was 58.61 ± 2.94 and in offspring 46.75 ± 2.54. In all 47.22 ± 11.53% families were found in high risk and 31.94 ± 10.77% in the moderate risk category. In female diabetics, the onset was in the age range of 41‑60 years.CONCLUSION:
We found a high‑risk of diabetes and familial clustering in successive generations of Brahmins with prominent male sex specificity. In females onset of diabetes was coinciding with the period around menopause.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Feminino
/
Humanos
/
Família
/
Prevalência
/
Medição de Risco
/
Adulto
/
Padrões de Herança
/
Grupos Populacionais
/
Diabetes Mellitus Tipo 2
/
Índia
Tipo de estudo:
Estudo de etiologia
/
Estudo de prevalência
/
Pesquisa qualitativa
/
Fatores de risco
País/Região como assunto:
Ásia
Idioma:
Inglês
Revista:
Indian J Hum Genet
Ano de publicação:
2013
Tipo de documento:
Artigo
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