Serological Correlation of Clinically Suspected Cases of Leptospirosis in Valsad, South Gujarat.

ABSTRACT

Leptospirosis is a zoonotic infection with worldwide significance and a re-emerging public health problem in India. Since early 1980”s the disease has been reported from various states during monsoon months. It is endemic in Gujarat, Andamans, Kerala, Tamil Nadu, Maharashtra, Karnataka and is also reported from Andhra Pradesh, West Bengal, Orissa, Puducherry, Delhi and Uttar Pradesh. Aim: Present study was undertaken to identify cases of Leptospirosis by Laboratory techniques. Materials and Methods: 136 samples have been considered for serological study in which 30 samples were taken as controls and 106 samples were of clinically suspected cases of leptospirosis. The study was conducted from July – October 2013 at our Tertiary care Hospital situated in South Gujarat. Serum samples of suspected cases of leptospirosis were collected and tested by Immunochromatography, IgM ELISA and MAT. Results: 63.20% of sera found to be positive for leptospirosis in which immunochromatography and IgM ELISA showed 66.98% and 66.98% positivity respectively. Conclusion: Study reveals that combination of IgM ELISA and MAT offer most reliable method for diagnosis of Leptospirosis.