Prevalence of inducible clindamycin resistance among community-associated staphylococcal isolates in central Serbia.
Indian J Med Microbiol
;
2014 Jan- Mar ; 32 (1): 49-52
Artigo
em Inglês
| IMSEAR
| ID: sea-156848
ABSTRACT
The emergence of resistance to most antimicrobial agents in staphylococci indicates the need for new effective agents in the treatment of staphylococcal infections. Clindamycin is considered to be one safe, effective and less costly agent. We analysed 482 staphylococcal isolates. Detection of inducible clindamycin resistance was performed by the D-test, while the presence of methylases genes erm (A), erm (B) and erm (C), as well as, macrolide effl ux gene mef was determined by polymerase chain reaction. Inducible clindamycin resistance phenotype was signifi cantly higher in Staphylococcus aureus (S. aureus) strains then in coagulase-negative staphylococci (CNS). Among analysed S. aureus isolates, the predominance of the erm (C) gene, followed by the erm (A) gene were detected. These results indicate that the D-test should be routinely performed on each staphylococcal isolates.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Tipo de estudo:
Estudo de prevalência
Idioma:
Inglês
Revista:
Indian J Med Microbiol
Assunto da revista:
Microbiology
Ano de publicação:
2014
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS