Hemophilus influenzae meningitis and septicaemia in a 14-month-old child after primary immunisation.

ABSTRACT

We report a 14-month-male child, who developed Hemophilus infl uenzae meningitis after three primary doses of the vaccine. The child presented with fever and seizures. H. infl uenzae was isolated from both cerebrospinal fl uid (CSF) and blood. The child also had features of septicaemia. Procalcitonin (104 ng/ml) and C-reactive protein (CRP - 42.6 mg/dl) were high. Appropriate antibiotics were given. The child made an uneventful recovery. This case highlights vaccine failure, especially after primary immunisation alone.