Cerebrospinal fluid N-acetyl neuraminic acid estimation for early diagnosis and differentiation of bacterial meningitis.
Indian Pediatr
;
1991 May; 28(5): 513-9
Artigo
em Inglês
| IMSEAR
| ID: sea-15717
ABSTRACT
Cerebrospinal fluid (CSF) analysis for free, bound and total N-Acetyl Neuraminic Acid (NANA) as well as serum NANA was done in 68 patients of bacterial meningitis, of which 37 cases were of pyrogenic meningitis and 31 of tuberculous meningitis. Ten patients were included in the control group. The free NANA levels were increased in only pyogenic meningitis, independent of protein levels but the bound form increased with the increase in CSF proteins. The increase of free NANA in CSF of pyogenic meningitis patients was not related to the cell count or sugar content in CSF or to the duration or severity of illness. This finding can be of great help in differentiating cases of pyogenic meningitis, particularly partially treated patients, who may have ambiguous pictures of CSF analysis, from the cases of tuberculous meningitis.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Valores de Referência
/
Ácidos Siálicos
/
Fatores de Tempo
/
Infecções Bacterianas
/
Tuberculose Meníngea
/
Humanos
/
Criança
/
Ácido N-Acetilneuramínico
/
Diagnóstico Diferencial
/
Meningite
Tipo de estudo:
Estudo diagnóstico
/
Estudo de rastreamento
Idioma:
Inglês
Revista:
Indian Pediatr
Ano de publicação:
1991
Tipo de documento:
Artigo
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