Changes in Microalbuminuria in Relation to Glycosylated Haemoglobin(HbAlc) and Duration in Type 2 Diabetes Mellitus.

ABSTRACT

Introduction: Diabetes Mellitus is a widely prevalent endocrine disease in the world and Nephropathy is one of the major complications that could lead to severe morbidity and mortality. Persistent microalbuminuria is the best predictor of development of macroalbuminuria and further development of end-stage renal disease as well as cardiovascular complications. The relation between microalbuminuria and glycosylated haemoglobin(HbA1c)as well as duration of diabetes are not clear and studies relating these parameters are few in our country. This study aims to understand this aspect. Aims & Objectives: Our objective is to observe the changes in microalbuminuria level in relation to various parameters of patients of type 2 Diabetes mellitus and to correlate the changes in microalbuminuria levels to HbA1c and duration of diabetes. Materials and Methods: The study was conducted in Medical College & Hospital, Kolkata. 40 patients of type 2 Diabetes mellitus fulfilling inclusion and exclusion criteria were included in this study. Results were analysed by SPSS software. Results: Microalbuminuria had positive correlation with BMI and Waist circumference (WC). No correlation was found between age and microalbuminuria.There was a significant and positive correlation found between microalbuminuria and duration of diabetes as well as microalbuminuria and HbA1c.