Your browser doesn't support javascript.
loading
Comparative evaluation of natural curcumin and synthetic chlorhexidine in the management of chronic periodontitis as a local drug delivery: A clinical and microbiological study.
Artigo em Inglês | IMSEAR | ID: sea-158244
ABSTRACT
Background of the Study The aim of this study is to evaluate the efficacy of natural curcumin in the management of chronic periodontitis as local drug delivery in comparison to synthetic chlorhexidine, which is the gold standard. Materials and

Methods:

Thirty chronic periodontitis patients with an age range of 20–50 years with probing pocket depth (PPD) of 4–6 mm were included. Curcumin and chlorhexidine gel was applied in the contralateral disease sites at baseline and day 15. The clinical parameters like PPD, clinical attachment level (CAL), gingival index (Loe and Silness) and plaque index (Turesky Gillmore modification of Quigley Hein) were recorded and colony forming units (CFU) were assessed microbiologically at baseline, 15 and 30 days.

Results:

There was a significant reduction of the clinical parameters (PPD, CAL) and microbiological parameters CFU at 15 and 30 days for both the groups. Curcumin group showed a greater reduction in the clinical parameters when compared with chlorhexidine group. Both groups had a significant reduction in parameters when compared with baseline.

Conclusion:

Although curcumin has equivalent benefit to chlorhexidine, curcumin being an ayurvedic herb is an excellent alternative to chlorhexidine due to minimal side‑effects.
Assuntos

Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Assunto principal: Doenças Periodontais / Feminino / Humanos / Masculino / Clorexidina / Sistemas de Liberação de Medicamentos / Adulto / Curcumina / Adulto Jovem / Pessoa de Meia-Idade Idioma: Inglês Ano de publicação: 2015 Tipo de documento: Artigo

Similares

MEDLINE

...
LILACS

LIS

Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Assunto principal: Doenças Periodontais / Feminino / Humanos / Masculino / Clorexidina / Sistemas de Liberação de Medicamentos / Adulto / Curcumina / Adulto Jovem / Pessoa de Meia-Idade Idioma: Inglês Ano de publicação: 2015 Tipo de documento: Artigo