Enzymatic modulation as a basis of therapeutics.

ABSTRACT

Enzyme inhibition has emerged as an important area in development of therapeutics. The basis of a large number of therapeutics used in modern day medicine for treatment of various aliments is enzyme inhibition. This review is a compilation of nearly all the therapeutic entities, currently in use, embracing almost each area of therapy including antibacterial, antifungal, antiviral, antimalarials, anticancer, antihypertensive, diuretics, antianginals, antithromboembolics, hypolipidemics, cardiotonics, anti-inflammatory, analgesics, antipyretics, antigout, antiasthamatics, antidepressants, cognition enhancers, antidiabetics, antithyroid drugs, drugs used for myasthenia gravis, peptic ulcer, parkinson’s disease, BHP, osteoarthritis, glaucoma, erectile dysfunction, septic shock, inflammation and/or neuro-degenerative disorders.