Salivary Biomarkers for Oral Squamous Cell Carcinoma: An Overview.
Artigo
em Inglês
| IMSEAR
| ID: sea-159393
ABSTRACT
Oral Cancer encompasses an important faction of neoplasms of head and neck. More than 90% of oral cancers are oral squamous cell carcinomas. Ideally, this fatal disease is detected through a comprehensive clinical examination by the oral health care professionals. Regardless of the fact that the oral cavity is easily accessible, most oral cancers are typically detected at an advanced stage. This has attributed to lower survival rate. Saliva, an aqueous biological fluid is in direct contact with the oral cancer lesion. Hence, the abnormal DNA, RNA, protein molecules released by the malignant cells can be easily obtained from saliva. Saliva, being a noninvasive diagnostic aid can be an alternative to serum for early detection, monitoring post therapy status, prognosis of oral cancer patients. This article aims to provide a brief overview of various salivary biomarkers and their implications in oral cancer.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Saliva
/
Neoplasias Bucais
/
Carcinoma de Células Escamosas
/
Biomarcadores
/
Análise de Sequência de RNA
/
Análise de Sequência de DNA
Tipo de estudo:
Estudo prognóstico
/
Estudo de rastreamento
Idioma:
Inglês
Ano de publicação:
2015
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS