Induction of lipid peroxidation by oxalate in experimental rat urolithiasis.
J Biosci
;
1987 Dec; 12(4): 367-373
Artigo
em Francês
| IMSEAR
| ID: sea-160613
ABSTRACT
The function of lipid peroxidation and the antiperoxidative enzymes of rat liver and kidney were studied in stone formation induced by intraperitoneal administration of sodium oxalate (7 mg/100 g body weight). The animals sacrificed 3 and 12 h after administration of sodium oxalate had higher level of malondialdehyde in liver and kidney than control animals. A significantly pronounced release of malondialdehyde was observed in treated liver and kidney homogenates when incubated with either ferrous sulphate or hydrogen peroxide compared to control liver and kidney. Superoxide dismutase activity was increased only in liver and not in kidney in treated animals compared to the control. A highly significant decrease in catalase activity was observed in both liver and kidney of treated animals.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Idioma:
Francês
Revista:
J Biosci
Ano de publicação:
1987
Tipo de documento:
Artigo
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