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Mechanism of initiation of yeast mitochondrial DNA replication: Role of RNA polymerase.
J Biosci ; 1997 Mar; 22(2): 149-159
Artigo em Inglês | IMSEAR | ID: sea-161105
ABSTRACT
Yeast mitochondrial RNA polymerase was purified and resolved into 2 distinct fractions. Peak A was found to be nonspecific and exhibited characteristics of the core polymerase, whereas peak Β exhibited characteristics of the holoenzyme. In vitro replication assays were carried out, using the peak Β enzyme, the cloned ori sequences and other DNA templates. It was found that ori 2 was the most efficient template for RNA polymerase primed DNA synthesis, as compared to all the other templates studied.

Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Idioma: Inglês Revista: J Biosci Ano de publicação: 1997 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: IMSEAR (Sudeste Asiático) Idioma: Inglês Revista: J Biosci Ano de publicação: 1997 Tipo de documento: Artigo