Treatment of Pityriasis Versicolor. A Comparative Study of Topical 4% Potassium Hydroxide Solution Versus 1% Clotrimazole Solution.
Br J Med Med Res
;
2013 Oct-Dec; 3(4): 2317-2324
Artigo
em Inglês
| IMSEAR
| ID: sea-163130
ABSTRACT
Aims:
To evaluate the effectiveness of topical 4% potassium hydroxide (KOH) solution in the treatment of pityriasis versicolor in comparison with topical 1% clotrimazole solution. StudyDesign:
Single-blinded, comparative therapeutic study. Place of the Study Department of Dermatology and Venereology – Baghdad Teaching Hospital-Baghdad, between June 2008 and August 2009.Methodology:
We included 90 patients divided into 2 groups group A (4% KOH), Includes 46 patients and group B (1% clotrimazole), and includes forty four patients. Skin scraping test was done for all patients. KOH was applied once daily, while clotrimazole solution twice daily for 2 or 4 weeks according to the response.Results:
Eighty patients completed the study; forty in each group. In group A, 31 (77.5%), 8(20%) and 1 (2.5%) patients showed complete, partial and no response respectively after 2 weeks. After 4 weeks, 39 (97.5%) patients showed complete response and 1 (2.5%) patients showed partial response. In group B, 20 (50%), 18 (45%) and 2 (5%) patients showed complete, partial response and no response respectively after 2 weeks. After 4 weeks, 38 (95%) patients showed complete response and 2 (5%) patients showed partial response. There was a significant difference at 2 weeks of treatment. Group A showing a better response than group B (p=0.02). Itching, burning sensation, and erythema were detected in few patients of both groups.Conclusion:
Topical 4% potassium hydroxide solution seems to act more rapidly than 1% clotrimazole solution for pityriasis versicolor.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Idioma:
Inglês
Revista:
Br J Med Med Res
Ano de publicação:
2013
Tipo de documento:
Artigo
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