Prospective evaluation of a rapid diagnostic test Typhidot for typhoid fever.
Artigo
em Inglês
| IMSEAR
| ID: sea-16329
ABSTRACT
BACKGROUND & OBJECTIVE:
Typhoid fever still continues to be a major public health problem around the world. A simple, reliable and affordable rapid diagnostic test has been a long felt need of the clinicians. We therefore prospectively evaluated the sensitivity and specificity of Typhidot test.METHODS:
The study was carried out between January 2002 and December 2003, on a total of 563 samples from patients clinically suspected to have typhoid fever; blood culture as well as serum for Typhidot test were received.RESULTS:
Of the 563 samples, Typhidot test and blood culture were positive in 36 patients, both the tests were negative for 503 patients. Typhidot test was positive for 9 patients with S. Paratyphi A infection. The sensitivity and specificity of the test using blood culture as gold standard were 92.3 and 98.8 per cent respectively for the typhoid fever. INTERPRETATION &CONCLUSION:
Typhidot test is rapid, easy to perform and reliable test for diagnosing typhoid fever, useful for small less equipped laboratories as well as for those with better facilities.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Assunto principal:
Salmonella paratyphi A
/
Salmonella typhi
/
Fatores de Tempo
/
Febre Tifoide
/
Humanos
/
Ensaio de Imunoadsorção Enzimática
/
Estudos Prospectivos
/
Sensibilidade e Especificidade
/
Febre Paratifoide
/
Reações Falso-Negativas
Tipo de estudo:
Estudo diagnóstico
/
Estudos de avaliação
/
Estudo observacional
Idioma:
Inglês
Ano de publicação:
2006
Tipo de documento:
Artigo
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