Evaluation of hypoglycemic effect of mangifera leaf.

ABSTRACT

From the time of immemorial people have used various plant extracts in their own ethnic therapeutic system. Mango (Mangifera indica) is adorned all over the world as a fruit. But these plants have some medicinal utility also. The present research work is done to evaluate the antidiabetic effect of mango leaf on albino rat. Phytochemical tests are made with ethanolic extract of mango leaf. Albino rats were treated with ethanolic plant extract at the dose of 100,200 and 400 mg/kg body weight respectively. Another group of diabetic rats are given standard insulin dose as hypoglycemic agent. The blood sugar levels are monitored separately for different groups at different time periods. A significant reduction in blood glucose level is observed at 200mg/kg level after four hours of leaf extract application. It shows that Mangifera leaf is almost equipotent to insulin in its ability to reduce blood sugar.