Synthesis, spectral and antimicrobial studies of some transition metal(II) complexes with schiff base 3-[(2-Hydroxy-6-Methoxyquinolin-3- Ylmethylene)-Amino]-2-Methyl-3h-Quinazoline-4-One.

ABSTRACT

The Complexes of the type ML2 and M¢L [where M= Cu(II), Co(II), Ni(II) and Mn(II); M¢= Zn(II), Cd(II) and Hg(II)] with the Schiff base ligand (HMeOQMAMQ) L=3-[(2-hydroxy-6-methoxyquinolin-3-ylmethylene)- amino]-2-methyl-3H-quinazoline-4-one, have been synthesized. Their characterizations have been done by elemental analysis, conductance data, magnetic susceptibility measurements, 1H NMR, electronic, IR, ESR and X-ray studies. Ligand field parameters of some of the complexes have also been calculated. On the basis of spectral studies, the complexes of Zn(II), Cd(II) and Hg(II) have been assigned tetrahedral geometry, where as complexes of Co(II), Ni(II) and Mn(II) have been assigned octahedral geometry, The complex of Cu(II) has been assigned distorted octahedral geometry. The Schiff base ligand and its complexes have also been screened for their antimicrobial activity against selected fungi and bacteria. The antimicrobial results indicate that the metal complexes act as better antimicrobial agents as compared to the Schiff base ligand.