Prevalence of biofilm producing MDR candida albicans and non candida albicans isolate from medical devices.

ABSTRACT

Totally 56% of occurrence was observed from 6 types of sources. Among them highest prevalence was observed from urinary catheter (68%) next in line is intravenous tubes (66.66%), venflon needles (65%), and blood bags (53.33%) respectively. Four types of Candida species were identified by using selective media and biochemical tests. The Candida albicans was predominant isolates in all sources especially in urinary catheter. In this study, 60.2% of non Candida albicans were observed. All isolates were subjected to antifungal stability test, 6 antifungal agents were used. Among the 6 antifungal agents Itraconazole had highly resistance activity and Fluconazole had highly sensitive activity against the isolates. The antifungal resistance of isolates were highly observed in non Candida albicans such as Candida tropicalis (83.3%) and followed by Candida glabrata (74.5%). All isolates were have the ability to produce biofilm, among them 37.4% of isolates were strong biofilm producer and 100% of protease producing isolates were observed in the last part of the study.