Evaluation of Antipyretic Potential of Pseudocedrela kotschyi Schweint. Harms (Meliaceae).
European J Med Plants
;
2013 Jan-Mar; 3(1): 105-113
Artigo
em Inglês
| IMSEAR
| ID: sea-164007
ABSTRACT
Pseudocedrela kotschyi is used in ethnomedicinal practice for the treatment of fever, pains and inflammation. The ethanol leaf extract of the plant was investigated for antipyretic potency in rats. Yeast and amphetamine induced hyperpyrexia were used to determine the antipyretic activity. The leaf extract (50, 100 and 150 mg/kg i.p.), exhibited significant (P<0.05) dose dependent effect on the tested experimental animal models of pyrexia. The LD50 was established to be 775 mg/kg, i.p. in mice. The results obtained suggest that the ethanol leaf extract may be a promising agent for the treatment of pyrexia.
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Índice:
IMSEAR (Sudeste Asiático)
Idioma:
Inglês
Revista:
European J Med Plants
Ano de publicação:
2013
Tipo de documento:
Artigo
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