Resolution of Bitot's Spots Following Mega-Dose Vitamin a Supplementation in Children between 1 and 5 Years of Age.
Artigo
em Inglês
| IMSEAR
| ID: sea-164538
ABSTRACT
Objectives:
To evaluate the responsiveness of BS over one year to MVAS administered as per national program in rural India.Methods:
Prospective community based follow-up of a cohort of 262 children with BS, aged between 1 and 5 years. Resolution or cure was defined if there was no discernible BS in either eye.Results:
During one year, only three children were lost to follow-up. At six months of follow-up (MVAS at baseline and 1 month later), 51.1% (95% CI 45.3% to 57.3%) were classified as cured. The corresponding figures at one year (additional MVAS at 6 months) were 59.9% (95% CI 54.1% to 65.9%). Amongst those cured at six months, about half and three-fourths had resolved at two and three months, respectively. There were no significant socio-demographic or clinical predictors of response.Conclusions:
Substantial non-response to MVAS at six months (49%) and one year (40%) of follow-up suggests that presently in the Indian subcontinent, Bitot's spot is a relatively crude indicator of severe current vitamin A deficiency. Thus for programmatic decisions and evaluation, public health burden of VAD should not be solely assessed through BS.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Tipo de estudo:
Estudo prognóstico
Idioma:
Inglês
Ano de publicação:
2015
Tipo de documento:
Artigo
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