Community Acquired Bacterial Ocular Pathogens And Their Antibiotic Resistance In Western India.

ABSTRACT

Abstracts Background: Various type of ocular infections are responsible for increased prevalence of morbidity and blindness worldwide. Specific therapy of ocular infections often requires etiological diagnosis and antibiotic sensitivity profile for individual. Methodology: This study was conducted on 120 patients attending ophthalmology institute in tertiary care eye hospital. All patients were included consecutively after the initial clinical diagnosis of ocular infection. Brief clinical history and demographic data along with samples was collected and analyzed in proper manner in accordance with standard protocols. Results: Out of total 120 samples, 55 samples were positive for bacterial culture. Most common causative organism among gram negative isolates, was Pseudomonas (19/55) and in case of the gram positive isolates, was S. aureus (16/55). Maximum sensitivity was observed towards linezolid and vancomycin for gram positive isolates and for rest of others, imipenem and combinations antibiotics. Conclusion: The type and pattern of organisms that cause ocular infection changes over time. Antibiotics which have broad coverage, sensitivity and are effective enough to treat the common corneal pathogens should be used.