Study Of Nerve Conduction Velocity In Type II Diabetes Mellitus.

ABSTRACT

Abstract Background& Objectives: Diabetic neuropathy is the most common and troublesome complication of diabetes mellitus, leading to great morbidity and resulting in burden for diabetes care. The progression of neuropathy can be reduced by early detection and intervention. Nerve conduction studies are the most sensitive indices of the severity of neuropathy. These tests can be used to localize lesions and describe the type and severity of the pathophysiologic process, including alterations that are not recognized clinically. This study was undertaken to compare nerve conduction study results in diabetes mellitus patients with good glycemic control and poor glycemic control and to compare it with non-diabetic subjects. This study aims to signify the role of nerve conduction study in diabetes mellitus. This can help in identifying the asymptomatic stage of diabetic neuropathy so that suitable preventive measures can be taken. Methodology: Total 90 subjects were included in the study group. 30 were non diabetic subjects and 60 were known cases of Type II diabetes mellitus patients attending diabetic OPD at GMCH, Aurangabad of age 30-50 years with duration of 5-10 years. Glycated haemoglobin levels were estimated and on this basis the cases were divided into two groups; diabetic patients with good glycemic control and diabetic patients with poor glycemic control. Nerve Conduction parameters were measured by computerized micromed RMSEMG system. Results: There was an increase in mean latency and decrease in amplitude and velocity values in both the diabetic groups. Intergroup comparison showed that, the increase in latency and decrease in amplitude and velocity was more in diabetics with poor glycemic control as compared to other study groups and this difference was statistically highly significant. Conclusion: The study concluded that there is statistically significant changes in nerve conduction parameters in Type II diabetes.