Bubble CPAP for Respiratory Distress Syndrome in Preterm Infants.
Indian Pediatr
;
2010 Feb; 47(2): 139-143
Artigo
em Inglês
| IMSEAR
| ID: sea-168403
ABSTRACT
Objectives:
To ascertain the immediate outcome of preterm infants with respiratory distress syndrome (RDS) on Bubble CPAP and identify risk factors associated with its failure. Studydesign:
Prospective analytical study.Subjects:
Inborn preterm infants (gestation 28 to 34 weeks) admitted to the NICU with respiratory distress and chest X- ray suggestive of RDS. Intervention Bubble CPAP with bi-nasal prongs. Primaryoutcome:
CPAP failures-infants requiring ventilation in the first one week.Results:
56 neonates were enrolled in the study. 14 (25%) babies failed CPAP. The predictors of failure were; no or only partial exposure to antenatal steroids, white-out on the chest X-ray, patent ductus arteriosus, sepsis/ pneumonia and Downe's score >7 or FiO2 ≥50% after 15- 20 minutes of CPAP. Other maternal and neonatal variables did not influence the need for ventilation. Rates of mortaility and duration of oxygen requirement was significantly higher in babies who failed CPAP. Only two infants developed pneumothorax. No baby had chronic lung disease.Conclusion:
Infants with no or partial exposure to antenatal steroids, white-out chest X-ray, patent ductus arteriosus, sepsis/pneumonia and those with higher FiO2 requirement after initial stabilization on CPAP are at high risk of CPAP failure (needing mechanical ventilation). Bubble CPAP is safe for preterm infants with RDS.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Tipo de estudo:
Estudo prognóstico
/
Fatores de risco
Idioma:
Inglês
Revista:
Indian Pediatr
Ano de publicação:
2010
Tipo de documento:
Artigo
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