Plasma Efavirenz in HIV-Infected Children Treated with Generic Antiretroviral Drugs in India.

ABSTRACT

We measured plasma concentration of efavirenz (EFV) in 16 HIV-infected Indian children receiving antiretroviral treatment at Government ART centres. The mean 12-hour concentration was 2.39 μg/mL (range 0.72- 7.82 μg/mL). The majority of children treated with generic EFV at currently recommended doses had blood levels within the therapeutic range.