Pigmented Basal Cell Carcinoma: A Case Report.

ABSTRACT

Basal cell carcinoma (BCC) which is also known as rodent ulcer is the most common type of skin cancer. Prolonged exposure to high-intensity ultraviolet radiation is regarded as the most common risk factor of BCC. This ionizing radiation can induce DNA damage such as point mutations, and single stranded DNA breaks. Other possible pathogenic mechanism includes the involvement of the tumor suppresser gene, and the members of sonic hedgehog signal transduction pathway. Pigmented BCC (PBCC) is a rare variant of BCC, of which only very few cases have been reported in literature. This is a case report of such a case of PBCC.