Comparison of Analgesic Effect of Direct Breastfeeding, Oral 25% Dextrose Solution and Placebo during 1st DPT Vaccination in Healthy Term Infants: A Randomized, Placebo Controlled Trial.
Indian Pediatr
;
2013 July; 50(7): 649-653
Artigo
em Inglês
| IMSEAR
| ID: sea-169881
ABSTRACT
Objective:
To compare analgesic effect of direct breast feeding, 25% dextrose solution and placebo as we give 1st intramuscular whole cell DPT injection to 6week - 3month old infants.Design:
Randomized, placebo controlled trial.Setting:
Immunization clinic of Department of Pediatrics, LLRM Medical College.Participants:
Infants coming for their 1st DPT vaccination were randomized in to three groups of 40 each. Outcomemeasures:
The primary outcome variable was the duration of cry after vaccination. Secondary outcome variables were Modified Facial Coding Score (MFCS) and latency of onset of cry.Results:
120 babies were equally enrolled in breast feed group, 25% dextrose fed group and distilled water fed group. Median (interquartile range) of duration of cry was significantly lower in breast fed (33.5 (17-54) seconds) and 25% dextrose fed babies (47.5 (31-67.5) seconds) as compared to babies given distilled water (80.5 (33.5-119.5) seconds) (P<0.001). MFCS at 1 min and 3 min was significantly lower in direct breast fed and dextrose fed babies.Conclusions:
Direct breastfeeding and 25% dextrose act as analgesic in young infants undergoing DPT vaccination in young infants less than 3 month of age.
Texto completo:
DisponíveL
Índice:
IMSEAR (Sudeste Asiático)
Tipo de estudo:
Ensaio Clínico Controlado
Idioma:
Inglês
Revista:
Indian Pediatr
Ano de publicação:
2013
Tipo de documento:
Artigo
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